
Hyaluronic Acid (HA) Injections
Overview
Hyaluronic acid (HA) injections, also known as viscosupplementation, are designed to restore the joint’s natural lubrication and cushioning.
They are particularly effective in managing knee osteoarthritis, where joint wear and tear reduces the quality of natural synovial fluid, leading to stiffness, friction, and discomfort.
By supplementing this fluid, HA injections help the joint move more smoothly, easing pain and improving function.



What It Treats
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Mild-to-moderate osteoarthritis of the knee or other joints
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Patients who have not achieved adequate relief with conservative treatments (physiotherapy, oral medication, or lifestyle changes)
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Individuals seeking non-surgical pain relief before considering more invasive options like joint replacement
Common Brands
Synvisc®, Ostenil®, Hyalgan®, Durolane®, Crespine® Gel (HA with local anaesthetic)
All hyaluronic acid products offer effective relief for osteoarthritis symptoms by lubricating the joint, reducing friction, and supporting smoother movement.
However, Crespine® Gel provides an enhanced experience for some patients due to its unique combination of high-quality HA and a built-in local anaesthetic, making the injection more comfortable during administration and well-suited for patients who are sensitive or anxious about procedures.


How It Works
The injection is administered directly into the joint under ultrasound guidance for precise placement.
Hyaluronic acid mimics the natural fluid within your joints, increasing lubrication and reducing friction during movement.
This cushioning effect helps to relieve stiffness and discomfort, improving overall joint function.
Results vary, but patients often experience significant improvement lasting 12–24 months depending on individual activity levels and disease severity.
Benefits & Limitations
Benefits
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Non-surgical and minimally invasive treatment option
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Improves lubrication and reduces joint friction
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Decreases pain and enhances mobility in osteoarthritis
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Well-tolerated and low risk when performed under sterile, guided conditions
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May delay or reduce the need for surgery in some patients
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Crespine® Gel version offers a more comfortable injection experience
Limitations
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Provides temporary relief — typically lasting 12 to 24 months
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Effectiveness may vary between individuals and stages of arthritis
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Less effective in advanced or severely degenerated joints
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Multiple sessions may be required to maintain results
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Not a regenerative treatment — it does not repair cartilage or reverse osteoarthritis



Side Effects & Considerations
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Mild soreness, redness, or swelling at the injection site (resolves within 24–48 hours)
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Temporary increase in joint discomfort may occur after the injection (rare)
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Minimal risk of infection or allergic reaction when performed under sterile conditions
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Avoid vigorous activity for a few days post-treatment to prevent irritation
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Not suitable for individuals with severe joint infection, bleeding disorders, or known allergies to HA products
Procedure & Aftercare
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The procedure is performed as a simple outpatient treatment under local anaesthetic and ultrasound guidance for accuracy.
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Patients may resume most normal activities the same day, though heavy exercise or prolonged standing should be avoided for 24–48 hours.
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Rest the treated joint for the remainder of the day.
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Apply ice intermittently if mild swelling occurs.
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Avoid high-impact activities (e.g., running, jumping) for 2–3 days.
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Follow-up sessions may be scheduled based on symptom response and desired outcome.
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Improvements in comfort and mobility typically begin within 2–6 weeks and may continue to develop over several months.

